Cytotron ARTHRITIS Treatment

New non-surgical Osteo-arthritis treatment
Now knee joint cartilage can be regenerated and repaired by QMR based Tissue Engineering with Cytotron Therapy. QMR regenerates degenerated cartilage and relieves chronic pain and disability of Knee non-invasively with multi-frequency rotating quantum electromagnetic resonating beams. Many knees can be saved from knee replacement surgery.

Before treatment Xray and Three months post treatment

The increased gap between the upper bone (femur) and the lower bone (tibia) seen on x-ray signifies increased cartilage confirming regeneration of cartilage.

Medical summary: Mrs.SD, 57 years lady weighing 99 Kg had pain in both knee joints since 4 years with deformity. She walked with the aid of walking stick and required pain killer drugs almost daily. Three months after treatment she is off pain killers, deformity is better and is not dependent on walking stick. Progressive improvement is expected for up-to one year and more.

What is the mechanism of Quantum Magnetic Resonance (QMR) Tissue Engineering (Regeneration and Degeneration)?
QMR produces high power multi frequency rotating quantum electromagnetic resonating beams that can be 'focussed ' on the site required to be treated.

What is the Principle of QMR in Tissue Regeneration and Degeneration?
Rotational Field Quantum Magnetic Resonance (RFQMR) technology utilized highly complex quantum electromagnetic beams in the sub-radio and near-radio frequency spectrum. The beams are precisely controlled and focused onto tissues to alter the proton spin inside and outside the cells therein generating streaming voltage potentials. This alters cell membrane potential and "Jams" the "Command and Control" of the target tissue cells stimulating cartilage growth.

How does QMR work in Tissue Regeneration of the cartilage?
Like other tissues, bone and cartilage are constantly being built up and broken down by a variety of metabolic and physical influences. The major stimulus for bone and cartilage formation is a signal generated when these structures are subjected to tension or compression. This explains why bone atrophies in the absence of any significant pressure, such as weightlessness during space travel or immobilization in a cast. The transmission of this signal is also impaired following joint injury due to trauma or diseases such as Osteo-arthritis.

In other words, when you take a step, putting weight on the joint, the cartilage is compressed, the fluid gets displaced, and it carries with it mobile ions, the sodium ions, leaving behind the negatively charged proteoglycan carboxyl and sulfate ions. This generates an electric potential because you have "neutralized" negative charges. This is called a streaming potential.
QMR is designed to characterize and reproduce the required signal that initiates these regenerative activities even though they are at rest). by the induction of a spin in the hydrogen atoms thus creating a streaming potential in the extra cellular matrix (ECM) when bone or cartilage are placed under a load.

What are the results of the treated?
As reported in the Journal of the Indian Society of Aerospace Medicine by Wg Cdr VG Vasishta, Dr RV Kumar, and Surg Cdr LJ Pinto evaluation of Osteo-arthritis patients treated with QMR. Using the Knee Society Scoring System and dynamometry. there was a highly significant improvement in Pain Score, Total Knee Score, Total Functional Score, Range of Movement and force of extension and the improvement persisted after the treatment.

Almost all patients show subjective improvements and are out of all pain killers by the 4th exposure. Results are seen three months post treatment. By the end of the treatment, almost all of the patients can walk for 1 to 5 km, without pain. About 40% can squat down on the floor, which they could not do it earlier. Upon 30 days follow up 95% patients are almost normalized, can climb stairs without help
Objectively, radiological evidence shows visible changes, and graphical measurement reveled 1 to 3.5 mm growth in cartilage during 30 days follow-up.
Dynamometry showed that, the joint capacity had gone up from as less as 5 kg before exposure to 45 kg during 30 days follow-up.
Range of Motion, Extension Lag, Flexion Contracture, Joint Stability and Alignment were all very significantly improved when evaluated using knee society scoring.
These patients do not need knee replacement surgery any more.

Is the treatment painful?
No, the treatment is absolutely painless. Patients can even listen to music, see television or read during the treatment.

What does the treatment cost?
TREATMENT IS FREE TO THOSE THAT CANNOT AFFORD THE COST, you will need to travel to Bangalore India and arrange for your stay, meals and transporation during treatment. We do have accomodations available in Bangalore for $300 USD - this covers your meals and a place to stay for the 22 days of treatment.
All inclusive treatment cost in all other centers is priced by the center, please contact the center directly or email Client Service. You will need to arrange for your travel to your chosen treatment facility as well as your trip home and you will need a visa.

Patients interested in treatment should plan at least 30 days in advance, you will need to complete an intake form and request a visa for entering India. The travel to and from treatment is not included in the price nor is any additional procedures requested or required during your stay. All additional charges must be met prior to departure from our facility.

How is QMR therapy evaluated and what are the expected results?
Almost all patients show improvements
Most patients have no pain by 4th exposure.
Almost all patients can walk for 1 to 5 km,
40% can squat down on the floor
Upon 30 days follow up 95% patients are almost normalized, can climb stairs
X-rays / MRI shows 1 to 3.5 mm growth in cartilage during 30 days follow-up.
Dynamometry shows increased joint capacity from less than 5 kg before exposure to 45 kg during 30 days follow-up.
Range of Motion, Extension, Flexion, Joint Stability and Alignment improve significantly when evaluated using knee society scoring.

Comparison	Arthroscopy	Replacement	QMR
Procedure	Endoscopic treatment	Surgical prosthesis replacement	Purely external with beam of rays
Anaesthesia	Sometimes	Yes	Nil
Blood transfusion	No	May be	No
Scar of cut	Minor	Yes	No
Pain	Yes	Yes	No
Hospital stay	Few hours	Few days	½ hour daily
Return to work	In days	In days to weeks	Same day
Danger of procedure	+	++	Negligible
Anaesthesia unfit Patients	Possible	Not possible	Possible
Major complications	+	++	Negligible
Procedure deaths	Very Rare	Rare	Nil
Complications	+	++	Not known
Preventive effect	No	No	Yes
Tissue Regeneration	No	No	Often
Acceptance by patients	Reluctant due to risk & expenses	Reluctant due to risk & expenses	Very well accepted.
Acceptance by doctors	Accepted well	Accepted well	Reluctant - new & awareness lacking

Cytotron Arthritis FAQ

How many joints have you treated?
We have treated about 200 joints. (Updated on 21.09.2006)

Can rheumatoid arthritis (Rheumatoid Factor positive) patients be treated with Cytotron?
We have treated rheumatoid arthritis patients successfully enabling the patients to be off pain killer drugs and improved deformity. The initial results are good and time will tell how long the good effects will last.

Is not Knee replacement a good option?
We feel all surgery should be avoided as far as possible. All surgery has risk to life and this one single reason is enough to consider Cytotron a better option than joint replacement.
Furthur no surgery is successful in every patient. A failed surgery can cripple a patient for life and there is no other option left for the patient.
The life of the artificial joint is limited and a second replacement is less successful and lasts less.
Cytotron cannot be done in replaced joint.

What if RFQMR fails?
In the rare patient where RFQMR fails either next higher harmonic of RFQMR can be tried or knee replacement can done.

How long will the effect of RFQMR last and what after that?
RFQMR is a new technology and it is not possible to accurately predict the duration of benefit of RFQMR therapy. Like with knee replacement, bypass surgery, angioplasty stenting or any other therapy the duration of benefit depends on various factors known and unknown - hence varies from patient to patient. We guess that it should last for 5 to 10 years or more. Even if there is recurrence after a few years RFQMR can always be repeated or as a last resort knee replacement can be considered.

What exactly is Tissue Engineering?
Tissue Engineering is the field of altering, modifying, controlled reproduction and controlled regeneration and degeneration of biological tissue. Using Tissue engineering techniques, today it is possible to regenerate dying tissues and organs inside the body, grow new blood vessels, heal wounds or fix an adamant fracture, grow new cartilage or even teach a few lessons to cancerous cells that go into a multiplication spree.

How Tissue Engineering works?
Cytotron which is the world's first Rotational Field Quantum Magnetic Resonance (RFQMR) Generator to achieve this. We have the latest second generation RFQMR generator, that looks like a MRI machine, to produce high power multi frequency rotating quantum electromagnetic resonating beams from 288 special RFQMR guns with an aperture of 120 mm, that are precisely focused to the target area of repair. (The first generation RFQMR generators had only 96 guns and an aperture of 40mm.)

What are the future applications of RFQMR?
In future, RFQMR can prove effective as a non-invasive solution in the treatment of Osteoarthritis, relieving pain and disability due to trauma, temporo-mandibular joint disease, tinnitus, peridontal disease, carpal tunnel syndrome, osteoporosis, tendonitis and convalescence following surgical repair of ligaments, fresh bone fractures in elderly, aseptic necrosis, fibromyalgia, sciatica, post-polio syndrome, migraine, metatarsalgia, acute burns, immune deficiency disorders, drug resistant epilepsy, diabetic neuropathy, herniated disk, problem wound healing, Stimulation of Angiogenic Growth Factor and promoting Coronary and peripheral pro-angiogenesis and retarding the Angiogenic Growth Factor to promote Anti-Angiogenesis in Cancer, degenerating and destroying tumors, by cellular apoptosis (programmed cell death)
Another possible application of QMR could be Electroporation. Electroporation involves directly applying QMR pulses of millionths of a second duration and field strength of 100-1500 volts per centimeter to living cells. These pulses cause nanoscopic pores to open up through the cell's membrane. When the pulse stops, the pores close again, trapping the drug or DNA inside the cell. Electroporation can be carried out by applying the QMR pulses either directly to the target tissue to be treated in a living organism, or to cell suspensions and isolated organs. This application of QMR may go a long way, as it will open up the potential for new approaches to medical problems where successful treatment depends on finding ways for the therapeutic molecules to reach the cell interior. This includes - among others - treatments such as cancer chemotherapy, the delivery of DNA for gene therapy and DNA vaccines, the delivery of drugs for treating cardiac and vascular problems as well as the treatment of the eye disease. After more studies are completed, many other potential applications such as the treatment of haemophilia and other genetic defects or the treatment of cardiovascular diseases and the prevention of atherosclerosis can be explored.

What is the Principle of RFQMR in Tissue Regeneration and Degeneration?
The cellular mechanisms and processes involved are complex, RFQMR works on the principle of altering cell membrane potential and "Jamming" the "Command and Control" of the target tissue cells, by altering the proton spin in the inside and outside the cells.

How does RFQMR work in Tissue Regeneration of the cartilage?
Like other tissues, bone and cartilage are constantly being built up and broken down by a variety of metabolic and physical influences. The major stimulus for bone and cartilage formation is a signal generated when these structures are subjected to tension or compression. This explains why bone atrophies in the absence of any significant pressure, such as weightlessness during space travel or immobilization in a cast. The transmission of this signal is also impaired following joint injury due to trauma or diseases such as osteoarthritis. QMR is designed to characterize and reproduce the required signal that initiates these regenerative activities by the induction of a spin in the hydrogen atoms thus creating a streaming potential in the extra cellular matrix (ECM) when bone or cartilage are placed under a load.
In other words, when you take a step, putting weight on the joint, the cartilage is compressed, the fluid gets displaced, and it carries with it mobile ions, the sodium ions, leaving behind the negatively charged proteoglycan carboxyl and sulfate ions. This generates an electric potential because you have "unneutralised" negative charges. This is called a streaming potential. RFQMR can recreate this streaming potential and its restorative rewards in joints impaired due to disease or trauma even though they are at rest.

How does RFQMR work in Tissue Degeneration of the tumour?
In Degenerative RFQMR, like in the application of destruction of the tumor in a cancer patient, it is thought that the chromosomes, following the messages received as a result of the variations of potential (-70 to -90mV normal, -40 to -60 when infected, -20 to -30 in cancer and 0 when dead) in the cytoplasmic membrane, activate through electromechanical effects (stress responsive), the emission of messages by the genes that regulate cell dynamics for normal cell functions or for the mitochondrial activities for ATP production.
It is supposed that the excessive production of ATP is related to an alteration of the glycoproteinic sensors present on the mitochondrion membrane with consequent lowering of the impedance that in turn does not discriminate between the signals in frequency and activates the production of ATP in an almost continual way. The cancer cell would therefore go into mitosis due to the excess of ATP. RFQMR fields are used to act on the mitochondrial membrane, increasing the impedance of the glycoproteinic sensors through the lengthening of the polyglycidic chain. The spin of the RFQMR field is used to interfere with the communications between the genes and the protoplasmic glycoproteinic complexes involved in the promotion of cell mitosis.
By this the impedance of the mitochondrial membrane to the messages coming from the genes increase with the RFQMR treatment and with increase in the malignancy (the highest impedance for undifferentiated tumors). This is related to a greater alteration of the sensors of the undifferentiated tumors and therefore to their greater predisposition to the bond with polyglycidic chains. The undifferentiated cancer cells, because of the high impedance induced on the mitochondrial membrane by the RFQMR treatment, it stops producing ATP and therefore 'possibly' enter into apoptosis. Following the treatment the differentiated cancer cells have an impedance which is still sensitive to some messages coming from the chromosomes promoting the normal production of ATP, so these cells change their state of mitosis; however, they continue to live in a quiescent state (vegetative form of life). The normal cells are not influenced by the RFQMR radiation treatment as the impedance of their mitochondrial sensors is not modified and remain sensitive to messages that arrive from the chromosomes for the activation of the ATP synthesis.